Phenotypic states become increasingly sensitive to perturbations near a bifurcation in a synthetic gene network
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Phenotypic states become increasingly sensitive to perturbations near a bifurcation in a synthetic gene network
Microorganisms often exhibit a history-dependent phenotypic response after exposure to a stimulus which can be imperative for proper function. However, cells frequently experience unexpected environmental perturbations that might induce phenotypic switching. How cells maintain phenotypic states in the face of environmental fluctuations remains an open question. Here, we use environmental pertur...
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ژورنال
عنوان ژورنال: eLife
سال: 2015
ISSN: 2050-084X
DOI: 10.7554/elife.07935